Life sciences
Iatia Imaging's QPI provides a digital phase contrast solution in the life sciences above and beyond the capabilities of conventional lens-based solutions.
Segmentation
QPI provides an improved contrast mechanism enabling highly accurate cell segmentation. Unlike conventional phase contrast mechanisms, such as Differential Interference Contrast (DIC) or optical phase contrast, QPI provides quantitative phase data based on the optical thickness of the sample.
QPI provides cleaner and more accurate cell segmentation for automated cell analysis.
Digital DIC
QPI is able to digitally generate Differential Interference Contrast (DIC) images from its phase and amplitude output. QPI DIC images are insensitive to birefringent plastic cultureware, unlike conventional DIC, and can be generated free of sample absorption which may obscure detail.
QPI also generates other phase contrast images such as "phase" (contrast) and Hoffman Modulation Contrast.
QPI's absorption free DIC removes the effect of obscuring media such as stains, dirt and dust on the sample or in the optics.
Quantitative
QPI images quantitatively measure the optical thickness of the sample, making it suitable for cell volume determination/monitoring. Conventional phase imaging techniques, such as DIC do not provide this information.
No specialized optics
QPI uses two defocused brightfield images captured with standard digital cameras making QPI practical where specialized phase optics and hardware are impractical or cumbersome.
High speed processing
QPI is a rapid solution supporting live capture of 640x480 pixel images at 15 frames per second.
Product applications
GE Healthcare's IN Cell 1000